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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX16
All Species:
38.79
Human Site:
Y495
Identified Species:
65.64
UniProt:
O60231
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60231
NP_003578.2
1041
119264
Y495
S
E
R
T
V
L
R
Y
M
T
D
G
M
L
L
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
Y498
S
E
R
T
V
L
R
Y
M
T
D
G
M
L
L
Rhesus Macaque
Macaca mulatta
NP_001098636
1044
119602
Y498
S
E
R
T
V
L
R
Y
M
T
D
G
M
L
L
Dog
Lupus familis
XP_538827
1042
119346
Y496
S
E
R
T
V
L
R
Y
M
T
D
G
M
L
L
Cat
Felis silvestris
Mouse
Mus musculus
A2A4P0
1244
142553
Y684
S
P
E
T
V
I
K
Y
M
T
D
G
M
L
L
Rat
Rattus norvegicus
NP_997661
1044
119245
Y498
S
E
R
T
V
L
R
Y
M
T
D
G
M
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZI74
1231
137685
F578
A
R
G
G
A
L
L
F
C
T
V
G
I
L
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956318
1054
121479
Y508
S
E
R
T
I
L
K
Y
M
T
D
G
M
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609946
894
102815
S404
P
E
L
K
L
L
I
S
S
A
T
L
D
A
E
Honey Bee
Apis mellifera
XP_001122325
831
95330
A341
L
K
L
L
I
S
S
A
T
L
D
A
T
K
F
Nematode Worm
Caenorhab. elegans
O45244
1008
114272
Y460
S
E
K
T
V
L
K
Y
M
T
D
G
M
L
L
Sea Urchin
Strong. purpuratus
O17438
455
51461
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
Y610
G
P
D
T
V
I
K
Y
M
T
D
G
M
L
L
Baker's Yeast
Sacchar. cerevisiae
P24384
1145
129992
Y578
G
P
D
T
R
I
K
Y
M
T
D
G
M
L
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.4
97.2
N.A.
39.5
95.9
N.A.
N.A.
24.7
N.A.
72.7
N.A.
57
53.9
55.8
24.5
Protein Similarity:
100
99.7
99.5
98.8
N.A.
57.7
97.8
N.A.
N.A.
41.3
N.A.
85.6
N.A.
71.7
66.4
75.2
33.1
P-Site Identity:
100
100
100
100
N.A.
73.3
100
N.A.
N.A.
33.3
N.A.
86.6
N.A.
13.3
6.6
86.6
0
P-Site Similarity:
100
100
100
100
N.A.
86.6
100
N.A.
N.A.
53.3
N.A.
100
N.A.
20
20
100
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
40
36.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.5
57.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
66.6
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
0
8
0
8
0
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
15
0
0
0
0
0
0
0
79
0
8
0
0
% D
% Glu:
0
58
8
0
0
0
0
0
0
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% F
% Gly:
15
0
8
8
0
0
0
0
0
0
0
79
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
15
22
8
0
0
0
0
0
8
0
0
% I
% Lys:
0
8
8
8
0
0
36
0
0
0
0
0
0
8
0
% K
% Leu:
8
0
15
8
8
65
8
0
0
8
0
8
0
79
72
% L
% Met:
0
0
0
0
0
0
0
0
72
0
0
0
72
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
22
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
8
43
0
8
0
36
0
0
0
0
0
0
0
0
% R
% Ser:
58
0
0
0
0
8
8
8
8
0
0
0
0
0
0
% S
% Thr:
0
0
0
72
0
0
0
0
8
79
8
0
8
0
0
% T
% Val:
0
0
0
0
58
0
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
72
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _